ORGLIST:3-hydroxyglutarate

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From: Paul Krebaum (adhesivedoc$##$earthlink.net)
Date: Fri Sep 10 2004 - 03:04:12 EDT


Acetonedicarboxylic acid and its esters can be prepared from citric acid and
20% fuming H2SO4. See Organic Synthesis Coll. Vol. 1, pages 10-12 and
237-238.

Presumably the keto group of either the ester or the disodium salt of the
acid
could be reduced with NaBH4 or Pt/H2 to the alcohol.

--- Paul Krebaum
--- adhesivedoc$##$earthlink.net

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