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From: e.kruiswijk (b.kruiswijk$##$bbk.ac.uk)
Date: Tue Mar 02 2004 - 04:11:39 EST


Dear All,

In the macrolactonisation step of Verrucarin B, Roush et al, JOC 1983, 48,
758 and JOC 1984, 49, 1772. Pivaaloyl chloride and 4-pyrrolidino pyridine
are used for the macrolactonisation step. What is the mechanism here?

Thanks,

Bert.

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