ORGLIST: n-BuLi stability

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From: Merlin (medchem$##$adelphia.net)
Date: Fri Oct 19 2001 - 00:48:04 EDT


Has anyone conducted stability studies (or know of leading references) of
n-BuLi and BuBr? Specifically in regards to temperature (and other
parameters)?

Specifically for a Br to Li exchange (Lithio-halo). Subsequent quenching
would liberate the Lithium.

The current solvent is MTBE.

Thank you in advance.

Cheers!
--
George D. 'Merlin' McCallion
Associate Research Scientist
Chemical Development
Sanofi-Synthelabo Research
9 Great Valley Parkway
Malvern, PA 19355
United States

Office: 610.889.6294
Fax: 610.889.6367
E: George.McCallion$##$sanofi-synthelabo.com

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