From: Alison og Thomas H°yer (alihoyer$##$mobilixnet.dk)
Date: Mon Jan 29 2001 - 18:00:43 EST
I have found RCM to work fine for 5,6,7 and 8 membered rings, and it is =
known from the literature for larger rings.
In my cases, succes of the RCM depended on the substrate being =
The catalyst decomposes rather quickly upon warming, so if the =
conversion doesn't become total in a few hours, there is a problem.
In cases with allylic and homo-allylic substitution, the reaction worked =
Perhaps other functional groups in your compounds are the problem.
Removal of the last traces of metal after the reaction is more of a =
problem. I have had no succes in following Paquette's procedure for =
oxidizing Ruthenium in the crude product with lead tetraacetate.
Other suggestions, anybody?
ORGLIST - Organic Chemistry Mailing List
Website / Archive / FAQ: http://www.orglist.net/
List coordinator: Joao Aires de Sousa (jas$##$mail.fct.unl.pt)
This archive was generated by hypermail 2.1.4 : Fri Sep 19 2003 - 12:16:28 EDT